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What is the Advantage and Disadvantage of Distilled Monoglycerides

Author: Franke

Aug. 04, 2025

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Monoglycerides: What Are They and Are They Safe? - Healthline

Monoglycerides tend to occur in certain oils and processed foods. They’re generally safe to eat but are often found in foods that contain high levels of other fats and sodium.

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If you’ve been keeping an eye on your cholesterol levels or blood pressure, you might also be monitoring your triglyceride levels. Triglycerides aren’t the only glyceride out there, however. If you’ve ever noticed monoglycerides or diglycerides listed on food labels, you might be wondering whether you need to worry about them, too.

Continue reading to learn more.

All glycerides consist of a glycerol molecule and one or more fatty acid chains:

  • monoglycerides have one fatty acid chain
  • diglycerides have two fatty acid chains
  • triglycerides have three fatty acid chains

According to an evaluation by the World Health Organization (WHO), mono- and diglycerides make up approximately 1 percent of the glycerides you consume. They occur naturally in certain oils and are also found in processed foods.

Most of the fats you eat, including plant-based oils and animal fats, are made up of triglycerides. Triglycerides play an important role in heart health. Doctors usually check triglyceride levels during routine cholesterol tests.

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Enzymes in your body break triglycerides down into mono- and diglycerides during digestion. When mono- and diglycerides enter the bloodstream, they are transformed back into triglycerides.

Mono- and diglycerides are emulsifiers, which means they help oil and water to blend. As a result, they’re commonly used as food additives. Small quantities are often added to packaged and frozen foods to improve texture and stability, prevent oil from separating, and extend shelf life.

You’ll find mono- and diglycerides on the ingredient lists of packaged and processed foods. They may go by other names, including:

  • distilled mono- and diglycerides
  • ethoxylated mono- and diglycerides
  • mono- and diglyceride esters
  • diacylglycerol oil

Mono- and diglycerides can be found in processed foods such as:

  • bread
  • tortillas
  • baked goods
  • nut butters
  • margarine
  • shortening
  • mayonnaise
  • coffee creamers
  • frozen dinners
  • ice cream
  • frosting
  • whipped topping
  • candy
  • soft drinks
  • chewing gum
  • some processed meats and meat substitutes

Grocery store aisles aren’t the only place you’ll find these additives. Fast food chains and restaurants also serve menu items containing mono- and diglycerides. Common sources include:

  • margarine used for cooking
  • bread
  • breadsticks
  • buns
  • croissants
  • biscuits
  • tortillas
  • fries
  • ice cream
  • milkshakes
  • frappes

Mono- and diglycerides help oil and water to blend. Because of this, they can be used to improve the texture or consistency of foods. For example, they help:

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  • improve the consistency of margarine
  • prevent the oil in peanut butter from separating
  • give ice cream a creamier consistency
  • reduce stickiness in candy

In processed meats and sausages, they help to ensure fat is well-distributed.

They’re added to baked goods to slow the staling process. They also improve texture, ensuring bread is doughy and elastic.

Trace amounts of both mono- and diglycerides are naturally present in some seed-based oils, such as:

  • olive oil
  • grapeseed oil
  • cottonseed oil

Concentrations are low so they are difficult to isolate. Because of that, mono- and diglycerides are sourced through a chemical reaction that begins with a triglyceride-containing animal fat or vegetable oil. With the addition of heat and an alkaline catalyst, triglycerides rearrange into mono- and diglycerides. The result is a substance that contains a random mixture of mono-, di-, and triglycerides.

Next, mono- and diglycerides are separated through distillation. They may undergo further processing before they are added to your food.

The consumption of trans fat has been linked to an increased risk of heart disease and stroke. According to the Centers for Disease Control and Prevention, avoiding artificial trans fat consumption could prevent between 3,000 and 7,000 heart disease-related deaths in the United States each year. Learn more about good fats, bad fats, and heart disease.

Since , the U.S. Food and Drug Administration (FDA) has been taking steps to remove artificial trans fat from all foods. This includes a ban, announced in , on partially hydrogenated oils (PHOs). PHOs are the most ubiquitous source of trans fat in food. Food manufacturers have until to remove all trans fat from their products.

Mono- and diglycerides contain small amounts of trans fat. They’re classified as emulsifiers and not lipids, so the FDA ban doesn’t apply to them. As trans fat is phased out, food companies may turn to mono- and diglycerides as low-cost alternatives.

According to the FDA, mono- and diglycerides are generally recognized as safe. They can be used in food without limitation, provided the manufacturing process is satisfactory.

The Center for Science in the Public Interest also describes them as safe, while a WHO report indicates that there are no harmful effects associated with their consumption.

That doesn’t necessarily mean they’re good for you. Currently, there’s no way of knowing how much trans fat is in products with mono- and diglycerides listed on the label.

Food products with mono- and diglycerides are also likely to be high in other fats, as well as refined sugar and flour.

Want more information on Mono and Diglycerides? Feel free to contact us.

Monoglycerides: What are they, risks, and who should avoid them

Medical News Today has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical journals and associations. We only use quality, credible sources to ensure content accuracy and integrity. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.
  • CFR — Code of Federal Regulations Title 21. (, August 14)
    https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.
  • Glycerides (mono and di). (, January 27)
    https://www.ams.usda.gov/sites/default/files/media/Glycerides%20TR%.pdf
  • Rarokar, N. R., Menghani, S., Kerzare, D., & Khedekar, P. B. (, July 25). Progress in synthesis of monoglycerides for use in food and pharmaceuticals. Journal of Experimental Food Chemistry, 3(3), 1–6
    https://www.omicsonline.org/open-access/progress-in-synthesis-of-monoglycerides-for-use-in-food-andpharmaceuticals---.pdf
  • Younes, M., Aggett, P., Aguilar, F., Crebelli, R., Dusemund, B., Filipič, M., ... Lambré. C. (, November 10). Re‐evaluation of mono‐and di‐glycerides of fatty acids (E 471) as food additives. EFSA Journal, 15(11), e
    https://efsa.onlinelibrary.wiley.com/doi/full/10./j.efsa..

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